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My CartCAS：616-91-1
Molecular Formula：C5H9NO3S
Molecular Weight：163.19
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 616-91-1 |
| Name | Acetylcysteine |
| Molecular Formula | C5H9NO3S |
| Molecular Weight | 163.19 |
| Solubility | Soluble in Water/DMSO ≥20mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 210-498-3 |
| MDL | MFCD00004880 |
| SMILES | SC[C@@H](C(O)=O)NC(C)=O |
| InChIKey | PWKSKIMOESPYIA-BYPYZUCNSA-N |
| InChI | InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1 |
| PubChem CID | 12035 |
| Target Point | Reactive oxygen species (ROS) |
| Passage | Immunology & Inflammation |
| Background | Acetylcysteine， an n-acetyl-derivative of cysteine， is a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis， can be used to reduce the thickness of mucus， and has anti-influenza virus activity. |
| Biological Activity | Acetylcysteine是一种粘液溶解剂，可以减少粘液的厚度。[1-5] |
| Data Literature Source | [1]. Kalimeris K， et al. N-acetylcysteine ameliorates liver injury in a rat model of intestinal ischemia reperfusion. J Surg Res. 2016 Dec; 206 (2) :263-272 [2]. Ferrari G， et al. N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells. J Neurosci. 1995 Apr; 15 (4) :2857-66. [3]. Tsai JC， et al. Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells. J Biol Chem. 1996 Feb 16; 271 (7) :3667-70. [4]. Yan CY， et al. Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway. J Neurosci. 1998 Jun 1; 18 (11) :4042-9. [5]. Farr SA， et al. The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J Neurochem. 2003 Mar; 84 (5) :1173-83 |
| Unit | Bottle |
| Specification | 250mg 10mM*1mL in DMSO 10mM*1mL in Water 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Manual Download
您好，我用无菌水配制了NAC母液，细胞暴露时使用培养基稀释至所需浓度。发现2-10mM的NAC均能使本身为红色的培养基变成黄色，应该是NAC呈现酸性。请问此时需要调节其pH吗？又该如何调节呢？ 2023-05-24 09:26:46
Administrator您好，可以使用NaOH调节PH。