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My CartCAS：171179-06-9
Molecular Formula：C14H12BrN5
Molecular Weight：330.18
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 171179-06-9 |
| Name | PD158780 |
| Molecular Formula | C14H12BrN5 |
| Molecular Weight | 330.18 |
| Solubility | Soluble in DMSO ≥2mg/mL |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| Target Point | EGFR |
| Passage | Angiogenesis;Protein Tyrosine Kinase/RTK |
| Background | PD158780 is a potent EGFR family inhibitor. |
| Biological Activity | PD158780 is a potent EGFR family inhibitor with IC50s of 8 pM， 49， 52， 52 nM for EGFR， ErbB2， ErbB3， and ErbB4， respectively.[1] |
| Data Literature Source | [1]. Fry DW， et al. Biochemical and antiproliferative properties of 4-[ar(alk)ylamino]pyridopyrimidines， a new chemical class of potent and specific epidermal growth factor receptor tyrosine kinase inhibitor. Biochem Pharmacol. 1997 Oct 15;54(8):877-87. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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