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My CartReactivity：Human,Mouse
Application：IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：57152
Host：Rabbit
Qty：
Size：
| Name | Anti-SLURP1 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | IHC 1:50-200. |
| Target | SLURP1 |
| Background | Has an antitumor activity (PubMed:8742060).Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin (PubMed:14721776, PubMed:17008884).In vitro down-regulates keratinocyte proliferation;the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner (PubMed:14506129, PubMed:26905431).In T cells may be involved in regulation of intracellular Ca2+ signaling (PubMed:17286989).Seems to have an immunomodulatory function in the cornea (By similarity).The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation (PubMed:25168896). |
| Swiss Prot | P55000 |
| Gene ID | 57152 |
| Subcellular Location | Secreted |
| Immunogen | Recombinant protein of human SLURP1 |
| Public Immunogen Range | 1-104aa |
| Calculated MW | 11kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol, 0.03% Proclin300, 0.5% BSA, pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with SLURP1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human melanoma with SLURP1 antibody diluted at 1:100.
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