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My Cart> Antibodies > Primary Antibodies > Anti-Glutathione Peroxidase 4 Polyclonal AntibodyReactivity：Rat,Mouse,Human
Application：IHC,IF,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：2879
Host：Rabbit
Qty：
Size：
| Name | Anti-Glutathione Peroxidase 4 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-1000. IHC 1:50-100. IF 1:50-200. |
| Target | Glutathione Peroxidase 4 |
| Background | The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death. It is also required for normal sperm development; thus, it has been identified as a moonlighting protein because of its ability to serve dual functions as a peroxidase, as well as a structural protein in mature spermatozoa. Mutations in this gene are associated with Sedaghatian type of spondylometaphyseal dysplasia (SMDS). This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. |
| Swiss Prot | P36969 |
| Gene ID | 2879 |
| Subcellular Location | Cytoplasm Mitochondrion |
| Immunogen | A synthetic peptide of human GPX4 |
| Calculated MW | 22kDa |
| Observed MW | 17kDa |
| Purification Method | Affinity purification |
| Storage Buffer | Liquid in PBS containing 50% glycerol，150mM NaCl and 0.02% sodium azide，pH 7.4. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Mouse Human Rat |
| Application | WB IF IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with Glutathione Peroxidase 4 antibody diluted at 1:1000;Lane: HepG2,Mouse testis.
Immunohistochemistry of paraffin-embedded Human breast cancer with Glutathione Peroxidase 4 antibody diluted at 1:100.
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