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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > NVP-ACC789CAS：300842-64-2
Molecular Formula：C21H17BrN4
Molecular Weight：405.29
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 300842-64-2 |
| Name | NVP-ACC789 |
| Molecular Formula | C21H17BrN4 |
| Molecular Weight | 405.29 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CC1=C(C=C(C=C1)NC2=NN=C(C3=CC=CC=C32)CC4=CC=NC=C4)Br |
| InChIKey | GXWKSXUPEFVUOO-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H17BrN4/c1-14-6-7-16(13-19(14)22)24-21-18-5-3-2-4-17(18)20(25-26-21)12-15-8-10-23-11-9-15/h2-11，13H，12H2，1H3，(H，24，26) |
| PubChem CID | 6918616 |
| Target Point | VEGFR;PDGFR |
| Passage | Angiogenesis; Protein Tyrosine Kinase/RTK |
| Background | NVP-ACC789 is an inhibitor of VEGFR-1, VEGFR-2, VEGFR-3 and PDGFR-β. |
| Biological Activity | NVP-ACC789 is an inhibitor of human VEGFR-1， VEGFR-2 (mouse VEGFR-2)， VEGFR-3 and PDGFR-β with IC50s of 0.38， 0.02 (0.23)， 0.18， 1.4 μM， respectively.[1] |
| Data Literature Source | [1]. Tille JC， et al. Vascular endothelial growth factor (VEGF) receptor-2 antagonists inhibit VEGF- and basicfibroblast growth factor-induced angiogenesis in vivo and in vitro. J Pharmacol Exp Ther. 2001 Dec;299(3):1073-85. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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