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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > SR-18292CAS：2095432-55-4
Molecular Formula：C23H30N2O2
Molecular Weight：366.51
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light brown to brown Solid
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| CAS | 2095432-55-4 |
| Name | SR-18292 |
| Molecular Formula | C23H30N2O2 |
| Molecular Weight | 366.51 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light brown to brown Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD31657330 |
| SMILES | CC1=CC=C(C=C1)CN(CC(COC2=CC=CC3=C2C=CN3)O)C(C)(C)C |
| InChIKey | BNRANURXPKRRKP-UHFFFAOYSA-N |
| InChI | InChI=1S/C23H30N2O2/c1-17-8-10-18(11-9-17)14-25(23(2，3)4)15-19(26)16-27-22-7-5-6-21-20(22)12-13-24-21/h5-13，19，24，26H，14-16H2，1-4H3 |
| PubChem CID | 129896798 |
| Target Point | PGC-1α |
| Passage | Metabolic Enzyme&Protease |
| Background | SR-18292 is a PPARγ-coactivator 1α (PGC-1α) inhibitor that promotes PGC-1α acetylation and inhibits gluconeogenic gene expression. |
| Biological Activity | SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor， which increases PGC-1α acetylation， suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes.[1] |
| Data Literature Source | [1]. Sharabi K， et al. Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell. 2017 Mar 23;169(1):148-160.e15. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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