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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > CC-223CAS：1228013-30-6
Molecular Formula：C21H27N5O3
Molecular Weight：397.47
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 1228013-30-6 |
| Name | CC-223 |
| Molecular Formula | C21H27N5O3 |
| Molecular Weight | 397.47 |
| Solubility | Soluble in DMSO ≥3mg/mL |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28976054 |
| SMILES | CC(C)(C1=NC=C(C=C1)C2=CN=C3C(=N2)N(C(=O)CN3)C4CCC(CC4)OC)O |
| InChIKey | UFKLYTOEMRFKAD-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H27N5O3/c1-21(2，28)17-9-4-13(10-22-17)16-11-23-19-20(25-16)26(18(27)12-24-19)14-5-7-15(29-3)8-6-14/h4，9-11，14-15，28H，5-8，12H2，1-3H3，(H，23，24) |
| PubChem CID | 58298316 |
| Target Point | mTOR |
| Passage | PI3K/Akt/mTOR |
| Background | CC-223 is an effective mTOR kinase inhibitor that inhibits mTORC1 and mTORC2. |
| Biological Activity | Onatasertib (CC-223) is a potent， selective， and orally bioavailable inhibitor of mTOR kinase， with an IC50 value for mTOR kinase of 16 nM. Onatasertib inhibits both mTORC1 and mTORC2.[1] |
| Data Literature Source | [1]. Mortensen DS， et al. CC-223， a Potent and Selective Inhibitor of mTOR Kinase: In Vitro and In Vivo Characterization. Mol Cancer Ther. 2015 Jun;14(6):1295-305. |
| Unit | Bottle |
| Specification | 2mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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