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My Cart> Small Molecule Compounds > Anti-Infection > Antiviral > 2'-Deoxy-2'-fluoroguanosineCAS：78842-13-4
Molecular Formula：C10H12FN5O4
Molecular Weight：285.23
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 78842-13-4 |
| Name | 2'-Deoxy-2'-fluoroguanosine |
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.23 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00923832 |
| SMILES | C1=NC2=C(N1C3C(C(C(O3)CO)O)F)N=C(NC2=O)N |
| InChIKey | UXUZARPLRQRNNX-DXTOWSMRSA-N |
| InChI | InChI=1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4，6，9，17-18H，1H2，(H3，12，14，15，19)/t3-，4-，6-，9-/m1/s1 |
| PubChem CID | 135415565 |
| Target Point | Influenza Virus |
| Passage | Anti-infection |
| Background | 2 -Deoxy-2 -fluoroguanosine， a nucleoside analogue， is an effective inhibitor of influenza virus. |
| Biological Activity | 2′-Deoxy-2′-fluoroguanosine， a nucleoside analog， is a potent inhibitor of influenza virus strains， with an EC90 of <0.35 μM for influenza virus A and B strains. 2′-Deoxy-2′-fluoroguanosine significantly inhibits replication of influenza virus in the upper respiratory tract， resulting in amelioration of fever and nasal inflammation[1][2]. |
| IC50 | EC90: <0.35 μM (influenza virus A and B)[1] |
| Data Literature Source | [1]. Tisdale M，et，al. Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine. Antimicrob Agents Chemother. 1995 Nov;39(11):2454-8. [2]. Jakeman KJ，et，al. Efficacy of 2'-deoxy-2'-fluororibosides against influenza A and B viruses in ferrets. Antimicrob Agents Chemother. 1994 Aug;38(8):1864-7. |
| Unit | Bottle |
| Specification | 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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