{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > Carglumic AcidCAS：1188-38-1
Molecular Formula：C6H10N2O5
Molecular Weight：190.15
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 1188-38-1 |
| Name | Carglumic Acid |
| Molecular Formula | C6H10N2O5 |
| Molecular Weight | 190.15 |
| Solubility | Soluble in DMSO ≥3mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 601-569-3 |
| MDL | MFCD00047874 |
| SMILES | C(CC(=O)O)[C@@H](C(=O)O)NC(=O)N |
| InChIKey | LCQLHJZYVOQKHU-VKHMYHEASA-N |
| InChI | InChI=1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H，1-2H2，(H，9，10)(H，11，12)(H3，7，8，13)/t3-/m0/s1 |
| PubChem CID | 121396 |
| Target Point | carbamoyl phosphate synthetase 1 (CPS1) |
| Passage | Metabolic Enzyme&Protease |
| Background | Carglumic acid is a functional analogue of n-acetylglutamic acid (NAG) and activator of carbamoyl phosphate synthetase 1 (CPS1). |
| Biological Activity | Carglumic acid (N-Carbamyl-L-glutamic acid)， a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator， is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.[1] |
| Data Literature Source | [1]. Chen CT， et al. Carglumic acid promotes apoptosis and suppresses cancer cell proliferation in vitro and in vivo. Am J Cancer Res. 2015 Nov 15;5(12):3560-9. |
| Unit | Bottle |
| Specification | 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
