{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > DesloratadineCAS：100643-71-8
Molecular Formula：C19H19ClN2
Molecular Weight：310.82
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 100643-71-8 |
| Name | Desloratadine |
| Molecular Formula | C19H19ClN2 |
| Molecular Weight | 310.82 |
| Solubility | Soluble in DMSO ≥10mg/mL(Need ultrasonic) |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 638-878-8 |
| MDL | MFCD00871949 |
| SMILES | C1CC2=C(C=CC(=C2)Cl)C(=C3CCNCC3)C4=C1C=CC=N4 |
| InChIKey | JAUOIFJMECXRGI-UHFFFAOYSA-N |
| InChI | InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2，5-6，9，12，21H，3-4，7-8，10-11H2 |
| PubChem CID | 124087 |
| Target Point | Histamine Receptor |
| Passage | GPCR & G Protein;Neuronal Signaling;Immunology & Inflammation |
| Background | Desloratadine is a potent histamine H1 receptor antagonist. |
| Biological Activity | Desloratadine is a new， selective， H(1)-receptor antagonist that also has anti-inflammatory activity.Desloratadine is a non-sedating， clinically effective， anti-allergic therapy that has been shown to exhibit anti-inflammatory properties that extend beyond its ability to antagonize histamine at H(1)-receptor sites.[1-2] |
| Data Literature Source | [1]. Geha，R.S. and E.O. Meltzer，Desloratadine: A new，nonsedating，oral antihistamine. J Allergy Clin Immunol，2001. 107(4): p. 751-62. [2]. Schroeder，J.T.，et al.，Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. Clin Exp Allergy，2001. 31(9): p. 1369-77. |
| Unit | Bottle |
| Specification | 25mg 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
