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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > ZAP-180013CAS：873080-25-2
Molecular Formula：C19H17Cl2N3O4S
Molecular Weight：454.33
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 873080-25-2 |
| Name | ZAP-180013 |
| Molecular Formula | C19H17Cl2N3O4S |
| Molecular Weight | 454.33 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CCS(=O)(=O)C1=NC=C(C(=N1)C(=O)N(CC2=CC=C(C=C2)Cl)CC3=CC=CO3)Cl |
| InChIKey | GTWKIPDKVRLUKN-UHFFFAOYSA-N |
| InChI | InChI=1S/C19H17Cl2N3O4S/c1-2-29(26，27)19-22-10-16(21)17(23-19)18(25)24(12-15-4-3-9-28-15)11-13-5-7-14(20)8-6-13/h3-10H，2，11-12H2，1H3 |
| PubChem CID | 2988718 |
| Target Point | ZAP-70 |
| Passage | Immunology & Inflammation |
| Background | ZAP-180013 is a ZAP-70 inhibitor. ZAP-180013 inhibits the interaction of the ZAP-70 SH2 domain with the immunoreceptor tyrosine-based activation motif (ITAM). |
| Biological Activity | ZAP-180013 是一种 ZAP-70 抑制剂，其 IC50 值为 1.8 μM。[1] |
| IC50 | ZAP-70: 1.8μM(IC50) [1] |
| Data Literature Source | [1]. Visperas PR，et al. Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen. SLAS Discov. 2017 Mar;22(3):324-331. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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