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My CartCAS：176161-24-3
Molecular Formula：C15H19Cl2N3O4
Molecular Weight：376.24
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 176161-24-3 |
| Name | Maribavir |
| Molecular Formula | C15H19Cl2N3O4 |
| Molecular Weight | 376.24 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00945570 |
| SMILES | CC(C)NC1=NC2=CC(=C(C=C2N1C3C(C(C(O3)CO)O)O)Cl)Cl |
| InChIKey | KJFBVJALEQWJBS-XUXIUFHCSA-N |
| InChI | InChI=1S/C15H19Cl2N3O4/c1-6(2)18-15-19-9-3-7(16)8(17)4-10(9)20(15)14-13(23)12(22)11(5-21)24-14/h3-4，6，11-14，21-23H，5H2，1-2H3，(H，18，19)/t11-，12-，13-，14-/m0/s1 |
| PubChem CID | 471161 |
| Target Point | HCMV;EBV |
| Passage | Anti-infection |
| Background | It is an effective inhibitor of histone phosphorylation catalyzed by wild-type pUL97, and can effectively act on HCMV and Epstein-Barr virus (EBV). |
| Biological Activity | Maribavir 是一种野生型 pUL97 在体外催化组蛋白磷酸化抑制剂，其 IC50 值为 3 nM。Maribavir 对 HCMV 和 Epstein-Barr 病毒（EBV）具有抗病毒活性。[1-2] |
| Data Literature Source | [1]. Shannon-Lowe CD，et al. The effects of maribavir on the autophosphorylation of ganciclovir resistant mutants of the cytomegalovirus UL97 protein. Herpesviridae. 2010 Dec 7;1(1):4. [2]. Biron KK，et al. Potent and selective inhibition of human cytomegalovirus replication by 1263W94，a benzimidazole L-riboside with a unique mode of action. Antimicrob Agents Chemother. 2002 Aug;46(8):2365-72. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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