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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Membrane Transporter & Ion Channel > VU0810464CAS：2126040-21-7
Molecular Formula：C18H21ClFN3O
Molecular Weight：349.83
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 2126040-21-7 |
| Name | VU0810464 |
| Molecular Formula | C18H21ClFN3O |
| Molecular Weight | 349.83 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CC1=NN(C(=C1)NC(=O)CC2=CC(=C(C=C2)F)Cl)C3CCCCC3 |
| InChIKey | HNJJARDABGKWSO-UHFFFAOYSA-N |
| InChI | InChI=1S/C18H21ClFN3O/c1-12-9-17(23(22-12)14-5-3-2-4-6-14)21-18(24)11-13-7-8-16(20)15(19)10-13/h7-10，14H，2-6，11H2，1H3，(H，21，24) |
| PubChem CID | 146014436 |
| Target Point | GIRK |
| Passage | Membrane Transporter&Ion Channel |
| Background | It is an effective, selective non-urea protein-gated inward rectifier potassium channel (GIRK, Kir3) activator. |
| Biological Activity | VU0810464 是一种强效、选择性的非尿素 G 蛋白门控内向整流钾通道（GIRK、Kir3）激活剂。[1] |
| Data Literature Source | [1]. Vo BN，et al. VU0810464，a non-urea G protein-gated inwardly rectifying K+ (Kir 3/GIRK) channel activator，exhibits enhanced selectivity for neuronal Kir 3 channels and reduces stress-induced hyperthermia in mice. Br J Pharmacol. 2019 Jul;176(13):2238-2249. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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