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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > Trap-101 HydrochlorideCAS：1216621-00-9
Molecular Formula：C24H36ClN3O2
Molecular Weight：434.01
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 1216621-00-9 |
| Name | Trap-101 Hydrochloride |
| Molecular Formula | C24H36ClN3O2 |
| Molecular Weight | 434.01 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CCN1C2=CC=CC=C2N(C1=O)C3=C(CN(CC3)CC4CCCCCCC4)CO.Cl |
| InChIKey | YEVMLMQAMCKVSC-UHFFFAOYSA-N |
| InChI | InChI=1S/C24H35N3O2.ClH/c1-2-26-22-12-8-9-13-23(22)27(24(26)29)21-14-15-25(17-20(21)18-28)16-19-10-6-4-3-5-7-11-19;/h8-9，12-13，19，28H，2-7，10-11，14-18H2，1H3;1H |
| PubChem CID | 56972178 |
| Target Point | Opioid Receptor(NOP receptor) |
| Passage | GPCR & G Protein;Neuronal Signaling |
| Background | It is an effective, selective and competitive NOP receptor antagonist. |
| Biological Activity | Trap-101 hydrochloride 是一种 NOP 受体拮抗剂，对 NOP、μ-、κ- 和 δ-opioid receptor 的 pKi 值分别为 8.65、6.60、6.14 、<5。Trap-101 hydrochloride 可用于帕金森病的研究。[1] |
| Data Literature Source | [1]. Marti M，et al. The novel nociceptin/orphanin FQ receptor antagonist Trap-101 alleviates experimental parkinsonism through inhibition of the nigro-thalamic pathway: positive interaction with L-DOPA. J Neurochem. 2008 Dec;107(6):1683-96. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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