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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Onjisaponin BCAS：35906-36-6
Molecular Formula：C75H112O35
Molecular Weight：1573.67
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 35906-36-6 |
| Name | Onjisaponin B |
| Molecular Formula | C75H112O35 |
| Molecular Weight | 1573.67 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28124358 |
| SMILES | CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)C)OC4C(C(C(CO4)OC5C(C(C(C(O5)CO)O)O)O)O)O)O)O)OC(=O)C67CCC(CC6C8=CCC9C(C8(CC7)CO)(CCC1C9(CC(C(C1(C)C(=O)O)OC1C(C(C(C(O1)CO)O)O)O)O)C)C)(C)C)C)OC(=O)C=CC1=CC=C(C=C1)OC)O)O)O |
| InChIKey | QSTBHNPMHXYCII-KJCIHCEPSA-N |
| InChI | InChI=1S/C75H112O35/c1-30-44(81)48(85)53(90)63(99-30)107-59-58(105-43(80)17-12-33-10-13-34(97-9)14-11-33)32(3)101-67(60(59)108-64-56(93)51(88)57(31(2)100-64)106-62-52(89)47(84)40(28-98-62)104-65-54(91)49(86)45(82)38(26-76)102-65)110-69(96)74-21-20-70(4，5)24-36(74)35-15-16-41-71(6)25-37(79)61(109-66-55(92)50(87)46(83)39(27-77)103-66)73(8，68(94)95)42(71)18-19-72(41，7)75(35，29-78)23-22-74/h10-15，17，30-32，36-42，44-67，76-79，81-93H，16，18-29H2，1-9H3，(H，94，95)/b17-12+/t30-，31-，32+，36-，37-，38+，39+，40+，41+，42+，44-，45-，46+，47-，48+，49-，50-，51-，52+，53+，54+，55+，56+，57-，58-，59-，60+，61-，62-，63-，64-，65-，66-，67-，71+，72+，73-，74-，75-/m0/s1 |
| PubChem CID | 21669942 |
| Target Point | α-synuclein;huntingtin |
| Passage | Neuronal Signaling |
| Background | It has been reported that Onjisaponin B can promote autophagy and degradation of mutant α-synuclein and huntingtin in PC-12 cells, which can be used in related studies of Parkinsons disease and Huntingtons disease. |
| Biological Activity | Onjisaponin B 是一种从远志中提取的天然产物，能增强 PC-12 细胞的自噬作用，对帕金森病和亨廷顿病具有潜在的治疗作用。[1] |
| Data Literature Source | [1]. Wu AG，et al. Onjisaponin B derived from Radix Polygalae enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells. Int J Mol Sci. 2013 Nov 15;14(11):22618-41. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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