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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Xanthurenic AcidCAS：59-00-7
Molecular Formula：C10H7NO4
Molecular Weight：205.17
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to brown Solid
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| CAS | 59-00-7 |
| Name | Xanthurenic Acid |
| Molecular Formula | C10H7NO4 |
| Molecular Weight | 205.17 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light yellow to brown Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-410-1 |
| MDL | MFCD00006754 |
| SMILES | C1=CC2=C(C(=C1)O)NC(=CC2=O)C(=O)O |
| InChIKey | FBZONXHGGPHHIY-UHFFFAOYSA-N |
| InChI | InChI=1S/C10H7NO4/c12-7-3-1-2-5-8(13)4-6(10(14)15)11-9(5)7/h1-4，12H，(H，11，13)(H，14，15) |
| PubChem CID | 5699 |
| Target Point | mGluR |
| Passage | GPCR & G Protein |
| Background | Xanthurenic Acid activates the mGlu2/3 metabotropic glutamate receptor and acts as an agonist of the Group II metabotropic glutamate receptor during sensory transmission in the hypothalamus. |
| Biological Activity | Xanthurenic Acid 是色氨酸的一种代谢产物，是 mGlu2/3 Metabotropic 谷氨酸受体（mGlu2 和 mGlu3）激动剂。[1-2] |
| Data Literature Source | [1]. Copeland CS，et al. Actions of Xanthurenic acid，a putative endogenous Group II metabotropic glutamate receptor agonist，on sensory transmission in the thalamus. Neuropharmacology. 2013 Mar;66:133-42. [2]. Fazio F，et al. Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for Schizophrenia. Sci Rep. 2015 Dec 8;5:17799. |
| Unit | Bottle |
| Specification | 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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