{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > SKF38393 HClCAS：62717-42-4
Molecular Formula：C16H18ClNO2
Molecular Weight：291.77
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
Qty：
Size：
| CAS | 62717-42-4 |
| Name | SKF38393 HCl |
| Molecular Formula | C16H18ClNO2 |
| Molecular Weight | 291.77 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00069248 |
| SMILES | C1CNCC(C2=CC(=C(C=C21)O)O)C3=CC=CC=C3.Cl |
| InChIKey | YEWHJCLOUYPAOH-UHFFFAOYSA-N |
| InChI | InChI=1S/C16H17NO2.ClH/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11;/h1-5，8-9，14，17-19H，6-7，10H2;1H |
| PubChem CID | 147514 |
| Target Point | Dopamine Receptor |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | It is a selective agonist for the dopamine D1 receptor. |
| Biological Activity | SKF38393 HCl 是多巴胺 D1 受体（D1DR）的选择性激动剂，IC50 为 110 nM。[1] |
| Data Literature Source | [1]. Altar CA，et al. Picomolar affinity of 125I-SCH 23982 for D1 receptors in brain demonstrated with digital subtraction autoradiography. J Neurosci. 1987 Jan;7(1):213-22. [2]. Mayerhofer A，et al. Functional dopamine-1 receptors and DARPP-32 are expressed in human ovary and granulosa luteal cells in vitro. J Clin Endocrinol Metab. 1999 Jan;84(1):257-64. [3]. Muralikrishnan D，et al. SKF-38393，a dopamine receptor agonist，attenuates 1-methyl-4-phenyl-1，2，3，6-tetrahydropyridine-induced neurotoxicity. Brain Res. 2001 Feb 23;892(2):241-7. [4]. Bouron A，et al. The D1 dopamine receptor agonist SKF-38393 stimulates the release of glutamate in the hippocampus. Neuroscience. 1999;94(4):1063-70. |
| Unit | Bottle |
| Specification | 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
