Securinine
Cat.No:IS2750 Solarbio
CAS:5610-40-2
Molecular Formula:C13H15NO2
Molecular Weight:217.27
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Light yellow to yellow Solid
Qty:
Size:
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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > SecurinineCAS:5610-40-2
Molecular Formula:C13H15NO2
Molecular Weight:217.27
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Light yellow to yellow Solid
Qty:
Size:
| CAS | 5610-40-2 |
| Name | Securinine |
| Molecular Formula | C13H15NO2 |
| Molecular Weight | 217.27 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
| MDL | MFCD00867422 |
| SMILES | C1CCN2C(C1)C34CC2C=CC3=CC(=O)O4 |
| InChIKey | SWZMSZQQJRKFBP-WZRBSPASSA-N |
| InChI | InChI=1S/C13H15NO2/c15-12-7-9-4-5-10-8-13(9,16-12)11-3-1-2-6-14(10)11/h4-5,7,10-11H,1-3,6,8H2/t10-,11-,13+/m1/s1 |
| PubChem CID | 442872 |
| Target Point | GABA Receptor |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | It is a GABAA receptor antagonist. |
| Biological Activity | Securinine 是一种植物生物碱,也是一种 γ-氨基丁酸(GABA)受体拮抗剂。[1-2] |
| Data Literature Source | [1]. Stefanowicz-Hajduk J,et al. Securinine from Phyllanthus glaucus Induces Cell Cycle Arrest and Apoptosis in Human Cervical Cancer HeLa Cells. PLoS One. 2016 Oct 28;11(10):e0165372. [2]. Gupta K,et al. Securinine,a myeloid differentiation agent with therapeutic potential for AML. PLoS One. 2011;6(6):e21203. |
| Unit | Bottle |
| Specification | 5mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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