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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Pralidoxime ChlorideCAS：51-15-0
Molecular Formula：C7H9ClN2O
Molecular Weight：172.61
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 51-15-0 |
| Name | Pralidoxime Chloride |
| Molecular Formula | C7H9ClN2O |
| Molecular Weight | 172.61 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-080-9 |
| MDL | MFCD00011981 |
| SMILES | C[N+]1=CC=CC=C1C=NO.[Cl-] |
| InChIKey | HIGSLXSBYYMVKI-UHFFFAOYSA-N |
| InChI | InChI=1S/C7H8N2O.ClH/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H，1H3;1H |
| PubChem CID | 135445761 |
| Target Point | AChE |
| Passage | Neuronal Signaling |
| Background | It is an effective reactivator of acetylcholinesterase (AChE). The AChE inhibited by the nerve agent is reactivated by nucleophilic attack of the binding nerve agent phosphorous center by part of oxime. |
| Biological Activity | Pralidoxime Chloride 是一种强效的乙酰胆碱酯酶（AChE）再活化剂，也是有机磷中毒的解毒剂。[1-2] |
| Data Literature Source | [1]. Cadieux CL，et al. Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents. Chem Biol Interact. 2016 Nov 25;259(Pt B):133-141. [2]. Houzé P，et al. High Dose of Pralidoxime Reverses Paraoxon-Induced Respiratory Toxicity in Mice. Turk J Anaesthesiol Reanim. 2018 Apr;46(2):131-138. doi: 10.5152/TJAR.2018.29660. Epub 2018 Apr 1. |
| Unit | Bottle |
| Specification | 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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