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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > Phentolamine MesylateCAS：65-28-1
Molecular Formula：C18H23N3O4S
Molecular Weight：377.46
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 65-28-1 |
| Name | Phentolamine Mesylate |
| Molecular Formula | C18H23N3O4S |
| Molecular Weight | 377.46 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-604-6 |
| MDL | MFCD00134201 |
| SMILES | CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.CS(=O)(=O)O |
| InChIKey | OGIYDFVHFQEFKQ-UHFFFAOYSA-N |
| InChI | InChI=1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2，3)4/h2-8，11，21H，9-10，12H2，1H3，(H，18，19);1H3，(H，2，3，4) |
| PubChem CID | 91430 |
| Target Point | Adrenergic Receptor |
| Passage | Endocrinology & Hormones;GPCR & G Protein；Neuronal Signaling |
| Background | It is a non-selective alpha-adrenergic antagonist. |
| Biological Activity | Phentolamine Mesylate 是一种非选择性的 α1 和 α2 肾上腺素能受体阻滞剂，可扩张血管以降低外周血管阻力。[1-3] |
| Data Literature Source | [1]. Gould L，et al. Phentolamine. Am Heart J. 1976 Sep;92(3):397-402. [2]. Liu L，et al. Evidence for functional alpha 2D-adrenoceptors in the rat intestine. Br J Pharmacol. 1996 Mar;117(5):787-92. [3]. Pan L，et al. Phentolamine inhibits angiogenesis in vitro: Suppression of proliferation migration and differentiation of human endothelial cells. Clin Hemorheol Microcirc. 2017;65(1):31-41. [4]. Fioretti AC，et al. Renal and femoral venous blood flows are regulated by different mechanisms dependent on α-adrenergic receptor subtypes and nitric oxide in anesthetized rats. Vascul Pharmacol. 2017 Dec;99:53-64. |
| Unit | Bottle |
| Specification | 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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