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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > O-Phospho-L-serineCAS：407-41-0
Molecular Formula：C3H8NO6P
Molecular Weight：185.07
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 407-41-0 |
| Name | O-Phospho-L-serine |
| Molecular Formula | C3H8NO6P |
| Molecular Weight | 185.07 |
| Solubility | Soluble in Water(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 206-986-0 |
| MDL | MFCD00065935 |
| SMILES | C(C(C(=O)O)N)OP(=O)(O)O |
| InChIKey | BZQFBWGGLXLEPQ-REOHCLBHSA-N |
| InChI | InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7，8)9/h2H，1，4H2，(H，5，6)(H2，7，8，9)/t2-/m0/s1 |
| PubChem CID | 68841 |
| Target Point | mGluR |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | O-Phospho-L-serine is an agonist for mGluR4, mGluR6, mGluR7, and mGluR8, and an antagonist for mGluR1 and mGluR2. |
| Biological Activity | O-Phospho-L-serine 是 L-丝氨酸的前体物质，是mGluR4、mGluR6、mGluR7 和 mGluR8 的激动剂，mGluR1 的弱拮抗剂和 mGluR2 的强拮抗剂。[1-3] |
| Data Literature Source | [1]. Kang HJ，et al. Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptors. J Biol Chem. 2015 Jan 30;290(5):2870-8. [2]. Kang HJ，et al. Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channels. J Biol Chem. 2014 Oct 24;289(43):29961-74. [3]. Bailey TJ，et al. The inhibitor of phagocytosis，O-phospho-L-serine，suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina. Exp Eye Res. 2010 Nov;91(5):601-12. |
| Unit | Bottle |
| Specification | 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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