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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > Flunixin MegluminCAS：42461-84-7
Molecular Formula：C21H28F3N3O7
Molecular Weight：491.46
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 42461-84-7 |
| Name | Flunixin Meglumin |
| Molecular Formula | C21H28F3N3O7 |
| Molecular Weight | 491.46 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 255-836-0 |
| MDL | MFCD01725419 |
| SMILES | CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F.CNCC(C(C(C(CO)O)O)O)O |
| InChIKey | MGCCHNLNRBULBU-WZTVWXICSA-N |
| InChI | InChI=1S/C14H11F3N2O2.C7H17NO5/c1-8-10(14(15，16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12;1-8-2-4(10)6(12)7(13)5(11)3-9/h2-7H，1H3，(H，18，19)(H，20，21);4-13H，2-3H2，1H3/t;4-，5+，6+，7+/m.0/s1 |
| PubChem CID | 39212 |
| Target Point | COX |
| Passage | Immunology & Inflammation |
| Background | It is an effective cyclooxygenase inhibitor with anti-inflammatory and antipyretic activities. |
| Biological Activity | Flunixin meglumine 是一种环氧化酶 (COX) 抑制剂，对 COX-1 和 COX-2 的 IC50 值分别为 0.55 和 3.24 μM，具有抗炎作用。[1-2] |
| IC50 | COX-1: 0.55μM(IC50);COX-2: 3.24μM(IC50)[1] |
| Data Literature Source | [1]. Bryant CE，et al. Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nuclear factor kappa B. Am J Vet Res. 2003 Feb;64(2):211-5. [2]. Cheng Z，et al. Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. Inflammation. 1998 Aug;22(4):353-66. |
| Unit | Bottle |
| Specification | 200mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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