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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > DomperidoneCAS：57808-66-9
Molecular Formula：C22H24ClN5O2
Molecular Weight：425.91
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 57808-66-9 |
| Name | Domperidone |
| Molecular Formula | C22H24ClN5O2 |
| Molecular Weight | 425.91 |
| Solubility | Soluble in DMSO ≥3mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 260-968-7 |
| MDL | MFCD00069256 |
| SMILES | C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O |
| InChIKey | FGXWKSZFVQUSTL-UHFFFAOYSA-N |
| InChI | InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2，4-7，14，16H，3，8-13H2，(H，24，29)(H，25，30) |
| PubChem CID | 3151 |
| Target Point | Dopamine Receptor |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | Domperidone is a selective dopamine 2 receptor antagonist. |
| Biological Activity | Domperidone 是一种多巴胺-2 受体拮抗剂，有止吐和促胃液分泌的作用。[1] |
| Data Literature Source | [1]. Reddymasu SC，et al. Domperidone: review of pharmacology and clinical applications in gastroenterology. Am J Gastroenterol. 2007 Sep;102(9):2036-45. [2]. Stoetzer C，et al. Cardiotoxic Antiemetics Metoclopramide and Domperidone Block Cardiac Voltage-Gated Na+ Channels. Anesth Analg. 2017 Jan;124(1):52-60. |
| Unit | Bottle |
| Specification | 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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