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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > RevefenacinCAS：864750-70-9
Molecular Formula：C35H43N5O4
Molecular Weight：597.75
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥96%
Appearance：White to off-white Solid
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| CAS | 864750-70-9 |
| Name | Revefenacin |
| Molecular Formula | C35H43N5O4 |
| Molecular Weight | 597.75 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | ≥96% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28386316 |
| SMILES | CN(CCN1CCC(CC1)OC(=O)NC2=CC=CC=C2C3=CC=CC=C3)C(=O)C4=CC=C(C=C4)CN5CCC(CC5)C(=O)N |
| InChIKey | FYDWDCIFZSGNBU-UHFFFAOYSA-N |
| InChI | InChI=1S/C35H43N5O4/c1-38(34(42)29-13-11-26(12-14-29)25-40-19-15-28(16-20-40)33(36)41)23-24-39-21-17-30(18-22-39)44-35(43)37-32-10-6-5-9-31(32)27-7-3-2-4-8-27/h2-14，28，30H，15-25H2，1H3，(H2，36，41)(H，37，43) |
| PubChem CID | 11753673 |
| Target Point | mAChR |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | It is an effective mAChR antagonist with high affinity on M3 receptor. |
| Biological Activity | Revefenacin 是一种强效的 mAChR 拮抗剂；对 M3 受体具有高亲和力，Ki 为 0.18 nM。[1] |
| Data Literature Source | [1]. Steinfeld T，et al.In Vitro Characterization of TD-4208，a Lung-Selective and Long-Acting Muscarinic Antagonist Bronchodilator[C]//American Thoracic Society International Conference.2009. [2]. Pulido-Rios MT，et al. In vivo pharmacological characterization of TD-4208，a novel lung-selective inhaled muscarinic antagonist with sustained bronchoprotective effect in experimental animal models. J Pharmacol Exp Ther. 2013 Aug;346(2):241-50. |
| Unit | Bottle |
| Specification | 2mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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