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My CartCAS：224452-66-8
Molecular Formula：C30H47NO4S
Molecular Weight：517.76
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 224452-66-8 |
| Name | Retapamulin |
| Molecular Formula | C30H47NO4S |
| Molecular Weight | 517.76 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD11045316 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | Retapamulin is a topical antibiotic that binds Staphylococcus aureus and E. coli ribosomes. |
| Biological Activity | Retapamulin 是一种半合成的胸腺嘧啶衍生物，是一种局部抗生素用于治疗皮肤感染，可以结合大肠杆菌和金黄色葡萄球菌核糖体，Kd值为3 nM。[1-4] |
| Data Literature Source | [1]. Yan K，et al. Biochemical characterization of the interactions of the novel pleuromutilin derivative retapamulin with bacterial ribosomes. Antimicrob Agents Chemother. 2006 Nov;50(11):3875-81. [2]. Rittenhouse S，et al. Selection of retapamulin，a novel pleuromutilin for topical use. Antimicrob Agents Chemother. 2006 Nov;50(11):3882-5. [3]. Odou MF，et al. In vitro activity against anaerobes of retapamulin，a new topical antibiotic for treatment of skin infections. J Antimicrob Chemother. 2007 Apr;59(4):646-51. [4]. Champney WS，et al. Retapamulin inhibition of translation and 50S ribosomal subunit formation in Staphylococcus aureus cells. Antimicrob Agents Chemother. 2007 Sep;51(9):3385-7. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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