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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > RacecadotrilCAS：81110-73-8
Molecular Formula：C21H23NO4S
Molecular Weight：385.48
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 81110-73-8 |
| Name | Racecadotril |
| Molecular Formula | C21H23NO4S |
| Molecular Weight | 385.48 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00865520 |
| SMILES | CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2 |
| InChIKey | ODUOJXZPIYUATO-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H23NO4S/c1-16(23)27-15-19(12-17-8-4-2-5-9-17)21(25)22-13-20(24)26-14-18-10-6-3-7-11-18/h2-11，19H，12-15H2，1H3，(H，22，25) |
| PubChem CID | 107751 |
| Target Point | Neprilysin |
| Passage | Metabolic Enzyme&Protease |
| Background | It is an enkephalin (NEP) inhibitor. |
| Biological Activity | Racecadotril 是一种中性内肽酶（NEP）抑制剂，和活性代谢物 Thiorphan 抑制 NEP 的 Kis 值分别为 4500 和 6.1 nM。[1] |
| Data Literature Source | [1]. Eberlin M，et al. A comprehensive review of the pharmacodynamics，pharmacokinetics，and clinical effects of the neutral endopeptidase inhibitor racecadotril. Front Pharmacol. 2012 May 30;3:93. [2]. Griggs DW，et al. Pharmacologic Comparison of Clinical Neutral Endopeptidase Inhibitors in a Rat Model of Acute Secretory Diarrhea. J Pharmacol Exp Ther. 2016 May;357(2):423-31. |
| Unit | Bottle |
| Specification | 250mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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