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My CartCAS：51940-44-4
Molecular Formula：C14H17N5O3
Molecular Weight：303.32
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 51940-44-4 |
| Name | Pipemidic Acid |
| Molecular Formula | C14H17N5O3 |
| Molecular Weight | 303.32 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 257-530-2 |
| MDL | MFCD00057291 |
| SMILES | CCN1C=C(C(=O)C2=CN=C(N=C21)N3CCNCC3)C(=O)O |
| InChIKey | JOHZPMXAZQZXHR-UHFFFAOYSA-N |
| InChI | InChI=1S/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8，15H，2-6H2，1H3，(H，21，22) |
| PubChem CID | 4831 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | Pipemidic acid is a class of pyridine-pyrimidine antibiotics that are derivatives of piromidic acid and are active against Gram-negative and certain Gram-positive bacteria. |
| Biological Activity | Pipemidic Acid 是 Piromidic acid 的一种衍生物，是一种抗菌剂，可抑制 DNA 回旋酶。对包括铜绿假单胞菌在内的革兰氏阴性菌以及一些革兰氏阳性菌具有活性。可用于肠道、泌尿道和胆道感染的研究。[1-2] |
| Data Literature Source | [1]. Lacovino R，et al. β-Cyclodextrin inclusion complex to improve physicochemical properties of pipemidic acid: characterization and bioactivity evaluation. Int J Mol Sci. 2013 Jun 25;14(7):13022-41. [2]. Aoyama H，et al. Purification of Citrobacter freundii DNA gyrase and inhibition by quinolones. Antimicrob Agents Chemother. 1988 Jan;32(1):104-9. [3]. Shimizu M，et al. Pipemidic acid: absorption，distribution，and excretion. Antimicrob Agents Chemother. 1975 Apr;7(4):441-6. |
| Unit | Bottle |
| Specification | 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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