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My CartCAS：53716-50-0
Molecular Formula：C15H13N3O3S
Molecular Weight：315.35
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 53716-50-0 |
| Name | Oxfendazole |
| Molecular Formula | C15H13N3O3S |
| Molecular Weight | 315.35 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 258-714-5 |
| MDL | MFCD00133728 |
| SMILES | COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)C3=CC=CC=C3 |
| InChIKey | BEZZFPOZAYTVHN-UHFFFAOYSA-N |
| InChI | InChI=1S/C15H13N3O3S/c1-21-15(19)18-14-16-12-8-7-11(9-13(12)17-14)22(20)10-5-3-2-4-6-10/h2-9H，1H3，(H2，16，17，18，19) |
| PubChem CID | 40854 |
| Target Point | Parasite |
| Passage | Anti-infection |
| Background | It is a broad spectrum of benzimidazoles insecticidal compound. |
| Biological Activity | Oxfendazole 是Fenbendazole的亚砜形式，是一种广谱的苯并咪唑类驱虫药。[1] |
| Data Literature Source | [1]. Dewa Y，et al. Involvement of oxidative stress in hepatocellular tumor-promoting activity of oxfendazole in rats. Arch Toxicol. 2009 May;83(5):503-11. [2]. Gleizes C，et al. Inducing effect of oxfendazole on cytochrome P450IA2 in rabbit liver. Consequences on cytochrome P450 dependent monooxygenases. Biochem Pharmacol. 1991 Jun 15;41(12):1813-20. [3]. El-Makawy A，et al. Genotoxical，teratological and biochemical effects of anthelmintic drug oxfendazole Maximum Residue Limit (MRL) in male and female mice. Reprod Nutr Dev. 2006 Mar-Apr;46(2):139-56. [4]. Dewa Y，et al. Immunohistochemical analyses at the late stage of tumor promotion by oxfendazole in a rat hepatocarcinogenesis model. Arch Toxicol. 2011 Feb;85(2):155-62. [5]. Gokbulut C，et al. Comparative plasma disposition of fenbendazole，oxfendazole and albendazole in dogs. Vet Parasitol. 2007 Sep 30;148(3-4):279-87. |
| Unit | Bottle |
| Specification | 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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