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My CartCAS：269055-15-4
Molecular Formula：C20H15BrN6O
Molecular Weight：435.28
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 269055-15-4 |
| Name | Etravirine |
| Molecular Formula | C20H15BrN6O |
| Molecular Weight | 435.28 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD09837879 |
| SMILES | CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N |
| InChIKey | PYGWGZALEOIKDF-UHFFFAOYSA-N |
| InChI | InChI=1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H，1-2H3，(H3，24，25，26，27) |
| PubChem CID | 193962 |
| Target Point | Reverse Transcriptase |
| Passage | Anti-infection |
| Background | Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that can be used in HIV related studies. |
| Biological Activity | Etravirine 是一种用于治疗艾滋病的非核苷类逆转录酶抑制剂（NNRTI）。[1-2] |
| Data Literature Source | [1]. Andries K，et al. TMC125，a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1. Antimicrob Agents Chemother. 2004 Dec;48(12):4680-6. [2]. Lazzarin A，et al. Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised，double-blind，placebo-controlled trial. Lancet. 2007 Jul 7;370(9581):39-48. |
| Unit | Bottle |
| Specification | 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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