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My CartCAS：697761-98-1
Molecular Formula：C23H23ClFNO5
Molecular Weight：447.88
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 697761-98-1 |
| Name | Elvitegravir |
| Molecular Formula | C23H23ClFNO5 |
| Molecular Weight | 447.88 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD11846135 |
| SMILES | CC(C)C(CO)N1C=C(C(=O)C2=C1C=C(C(=C2)CC3=C(C(=CC=C3)Cl)F)OC)C(=O)O |
| InChIKey | JUZYLCPPVHEVSV-LJQANCHMSA-N |
| InChI | InChI=1S/C23H23ClFNO5/c1-12(2)19(11-27)26-10-16(23(29)30)22(28)15-8-14(20(31-3)9-18(15)26)7-13-5-4-6-17(24)21(13)25/h4-6，8-10，12，19，27H，7，11H2，1-3H3，(H，29，30)/t19-/m1/s1 |
| PubChem CID | 5277135 |
| Target Point | HIV Integrase |
| Passage | Anti-infection |
| Background | Elvitegravir is an HIV integrase inhibitor. |
| Biological Activity | Elvitegravir 是一种HIV抑制剂，作用于HIV-1 IIIB，HIV-2 EHO和HIV-2 ROD，无细胞试验中IC50 分别为0.7，2.8和1.4 nM。[1] |
| IC50 | HIV-1 IIIB: 0.7nM(IC50);HIV-2 ROD: 1.4nM(IC50);HIV-2 EHO: 2.8nM(IC50) [1] |
| Data Literature Source | [1]. Shimura K，et al. Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137). J Virol. 2008 Jan;82(2):764-74. [2]. Lampiris HW. Elvitegravir: a once-daily，boosted，HIV-1 integrase inhibitor. Expert Rev Anti Infect Ther. 2012 Jan;10(1):13-20. doi: 10.1586/eri.11.157. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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