{{cart_num}}
My CartCAS：62013-04-1
Molecular Formula：C42H78N2O14
Molecular Weight：835.07
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 62013-04-1 |
| Name | Dirithromycin |
| Molecular Formula | C42H78N2O14 |
| Molecular Weight | 835.07 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00865041 |
| SMILES | CCC1C(C2C(C(C(CC(C(C(C(C(C(=O)O1)C)OC3CC(C(C(O3)C)O)(C)OC)C)OC4C(C(CC(O4)C)N(C)C)O)(C)O)C)NC(O2)COCCOC)C)(C)O |
| InChIKey | WLOHNSSYAXHWNR-DWIOZXRMSA-N |
| InChI | InChI=1S/C42H78N2O14/c1-15-29-42(10，49)37-24(4)32(43-30(56-37)21-52-17-16-50-13)22(2)19-40(8，48)36(58-39-33(45)28(44(11)12)18-23(3)53-39)25(5)34(26(6)38(47)55-29)57-31-20-41(9，51-14)35(46)27(7)54-31/h22-37，39，43，45-46，48-49H，15-21H2，1-14H3/t22-，23-，24+，25+，26-，27+，28+，29-，30-，31+，32+，33-，34+，35+，36-，37-，39+，40-，41-，42-/m1/s1 |
| PubChem CID | 6473883 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | It is a macrolide glucopeptide antibiotic that inhibits peptide translocation by binding to the 50S subunit of the 70S ribosome of bacteria. |
| Biological Activity | Dirithromycin 是红霉素的衍生物，是一种强效口服活性半合成大环内酯类抗生素。地红霉素对革兰氏阳性菌、军团菌属、幽门螺旋杆菌和沙眼衣原体具有活性。[1-2] |
| Data Literature Source | [1]. Wasilewski MM，et al. Five-day dirithromycin therapy is as effective as seven-day erythromycin therapy for acute exacerbations of chronic bronchitis. J Antimicrob Chemother. 1999 Apr;43(4):541-8. [2]. Counter FT，et al. Synthesis and antimicrobial evaluation of dirithromycin (AS-E 136; LY237216)，a new macrolide antibiotic derived from erythromycin. Antimicrob Agents Chemother. 1991 Jun;35(6):1116-26. |
| Unit | Bottle |
| Specification | 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
The TonB system in Aeromonas hydrophila NJ-35 is essential for MacA2B2 efflux pump-mediated macrolide resistance
Click to check >>Author：Dong Y; Li Q; Geng J; Cao Q; Zhao D; Jiang M; Li S
IF：4.4000
Publish_to：Veterinary Research
PMID：33926565
Manual Download
