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My CartCAS：147221-93-0
Molecular Formula：C23H32N6O6S2
Molecular Weight：552.67
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 147221-93-0 |
| Name | Delavirdine Mesylate |
| Molecular Formula | C23H32N6O6S2 |
| Molecular Weight | 552.67 |
| Solubility | Soluble in DMSO ≥3mg/mL |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00866948 |
| SMILES | CC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)NS(=O)(=O)C.CS(=O)(=O)O |
| InChIKey | MEPNHSOMXMALDZ-UHFFFAOYSA-N |
| InChI | InChI=1S/C22H28N6O3S.CH4O3S/c1-15(2)24-19-5-4-8-23-21(19)27-9-11-28(12-10-27)22(29)20-14-16-13-17(26-32(3，30)31)6-7-18(16)25-20;1-5(2，3)4/h4-8，13-15，24-26H，9-12H2，1-3H3;1H3，(H，2，3，4) |
| PubChem CID | 441386 |
| Target Point | HIV |
| Passage | Anti-infection |
| Background | It is an effective non-nucleoside reverse transcriptase inhibitor (NNRTI), which selectively inhibits HIV-1 reverse transcriptase and is an inhibitor of HIV-1 virus replication, which can be used in AIDS related research. |
| Biological Activity | Delavirdine Mesylate 是一种强效、高特异性和口服活性非核苷类逆转录酶抑制剂（NNRTI）。可选择性地抑制 HIV-1 逆转录酶（RT）（IC50=0.26 μM），而不是 DNA 聚合酶 α（IC50=440 μM）和聚合酶 δ（IC50>550 μM）。是一种 HIV-1 复制抑制剂，可用于研究艾滋病。[1] |
| IC50 | HIV-1 RT: 026μM(IC50);DNA polymerase α: 440μM(IC50);DNA polymerase δ: >550μM(IC50)[1] |
| Data Literature Source | [1]. Dueweke TJ，et al. U-90152，a potent inhibitor of human immunodeficiency virus type 1 replication. Antimicrob Agents Chemother. 1993 May;37(5): 1127-31. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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