Anti-RAPGEF1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K111587P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-RAPGEF1 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2889 | 【Swiss Prot】：Q13905 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human RAPGEF1 | |
| 【Public Immunogen Range】：465-515/1077aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.
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