Anti-HSD17B11 Polyclonal Antibody
Cat: K111476P
Summary:
| 【Product name】：Anti-HSD17B11 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51170 | 【Swiss Prot】：Q8NBQ5 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000;IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human HSD17B11 | |
| 【Public Immunogen Range】：85-135/300aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
Verified picture:
Western blot analysis with HSD17B11 antibody diluted at 1:2000;Lane: HepG2,THP-1,L-02,HMC1.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with HSD17B11 antibody diluted at 1:100.