Anti-SPART Polyclonal Antibody
Cat: K111008P
Summary:
| 【Product name】：Anti-SPART Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23111 | 【Swiss Prot】：Q8N0X7 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human SPART | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]
Verified picture:
Western blot analysis with SPART antibody diluted at 1:3000;Lane: NIH/3T3,293T,HeLa.
Immunohistochemistry of paraffin-embedded Human endometrial cancer with SPART antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human thyroid cancer with SPART antibody diluted at 1:100.