Anti-LRSAM1 Polyclonal Antibody
Cat: K110743P
Summary:
| 【Product name】：Anti-LRSAM1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：90678 | 【Swiss Prot】：Q6UWE0 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human LRSAM1 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. Bacterial recognition protein that defends the cytoplasm from invasive pathogens. Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy).
Verified picture:
Western blot analysis with LRSAM1 antibody diluted at 1:2000;Lane: Jurkat,HepG2,A431,MCF7,PC-3,COS7.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with LRSAM1 antibody diluted at 1:200.