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Anti-SOCS6 Polyclonal Antibody
Cat: K009908P
Summary:
【Product name】:Anti-SOCS6 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9306 【Swiss Prot】:O14544
【Tested applications】:IHC,ELISA,WB
【Recommended dilution】:WB 1:500-2000. IHC 1:50-200. ELISA 1:5000-10000.
【Immunogen】:Recombinant protein of human SOCS6
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
Verified picture:
Western blot analysis with SOCS6 antibody diluted at 1:1000;Lane: Jurkat,293T,HeLa,Mouse liver.
Immunohistochemistry of paraffin-embedded Human liver cancer with SOCS6 antibody diluted at 1:100.