下载
Anti-CHGA Polyclonal Antibody
Cat: K009894P
Summary:
【Product name】:Anti-CHGA Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity Purification
【Gene ID】:1113 【Swiss Prot】:P10645
【Tested applications】:WB,ELISA,IHC
【Recommended dilution】:WB 1:500-2000. IHC 1:25-100. ELISA 1:2000-5000.
【Immunogen】:A synthetic peptide of human CHGA
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with CHGA antibody diluted at 1:1000;Lane: A549,293T,Human normal kidney,HeLa.
Immunohistochemistry of paraffin-embedded Human liver cancer with CHGA antibody diluted at 1:50.