Anti-LZTS1 Polyclonal Antibody
Cat: K009889P
Summary:
| 【Product name】：Anti-LZTS1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity Purification |
| 【Gene ID】：11178 | 【Swiss Prot】：Q9Y250 |
| 【Tested applications】：WB,IHC,ELISA | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:10-50. ELISA 1:1000-2000. | |
| 【Immunogen】：A synthetic peptide of human LZTS1 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Verified picture:
Western blot analysis with LZTS1 antibody diluted at 1:500;Lane: Mouse spleen.
Immunohistochemistry of paraffin-embedded Human liver cancer with LZTS1 antibody diluted at 1:40.