Anti-Sur-8 Polyclonal Antibody - HRP
Cat: K009780P - HRP
Summary:
| 【Product name】：Anti-Sur-8 Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8036 | 【Swiss Prot】：Q9UQ13 |
| 【Tested applications】：WB,IHC,IF,ELISA | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：Recombinant protein of human Sur-8 | |
| 【Public Immunogen Range】：235-583aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
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