Anti-CHP2 Polyclonal Antibody
Cat: K110288P
Summary:
| 【Product name】：Anti-CHP2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：63928 | 【Swiss Prot】：O43745 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human CHP2 | |
| 【Public Immunogen Range】：30-80/196aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.
Verified picture:
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with CHP2 antibody diluted at 1:200.