Anti-CD44 Polyclonal Antibody
Cat: K009692P
Summary:
| 【Product name】：Anti-CD44 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：960 | 【Swiss Prot】：P16070 |
| 【Tested applications】：WB,IHC,ELISA | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. | |
| 【Immunogen】：A synthetic peptide of human CD44 | |
| 【Public Immunogen Range】：701-742/742aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
Verified picture:
Western blot analysis with CD44 antibody diluted at 1:1000;Lane: Hela Panc-1 Huvec A549.