Anti-BACE1 Polyclonal Antibody - SAlexa Fluor 555
Cat: K009457P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-BACE1 Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23621 | 【Swiss Prot】：P56817 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human BACE1 | |
| 【Public Immunogen Range】：401-501/501aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
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