Anti-ACVR1C Polyclonal Antibody
Cat: K108715P
Summary:
| 【Product name】：Anti-ACVR1C Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：130399 | 【Swiss Prot】：Q8NER5 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of Human ACVR1C | |
| 【Public Immunogen Range】：340-390/493aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Verified picture:
Western blot analysis with ACVR1C antibody diluted at 1:4000;Lane: SH-SY5Y,HEK293,A431,HMC1.
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with ACVR1C antibody diluted at 1:50.