Anti-FOXO4 Polyclonal Antibody
Cat: K108702P
Summary:
| 【Product name】：Anti-FOXO4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4303 | 【Swiss Prot】：P98177 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of Human FOXO4 | |
| 【Public Immunogen Range】：70-120/505aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Verified picture:
Western blot analysis with FOXO4 antibody diluted at 1:2000;Lane: HeLa,HUVEC,Mouse heart.