Anti-PTH1R Polyclonal Antibody
Cat: K108192P
Summary:
| 【Product name】：Anti-PTH1R Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5745 | 【Swiss Prot】：Q03431 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human PTH1R | |
| 【Public Immunogen Range】：27-189aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene
Verified picture:
Western blot analysis with PTH1R antibody diluted at 1:4000;Lane: Mouse kidney,Mouse liver.
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with PTH1R antibody diluted at 1:50.