Anti-IL2RA Polyclonal Antibody
Cat: K107601P
Summary:
| 【Product name】：Anti-IL2RA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3559 | 【Swiss Prot】：P01589 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human IL2RA | |
| 【Public Immunogen Range】：145-195/272aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with IL2RA antibody diluted at 1:100.