Anti-TNFRSF4 Polyclonal Antibody
Cat: K107600P
Summary:
| 【Product name】：Anti-TNFRSF4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7293 | 【Swiss Prot】：P43489 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-1:3000. | |
| 【Immunogen】：A synthetic peptide of human TNFRSF4 | |
| 【Public Immunogen Range】：100-150/277aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Verified picture:
Western blot analysis with TNFRSF4 antibody diluted at 1:2000;Lane: HT29,Mouse thymus.