Anti-PPARK2/Parkin Monoclonal Antibody - Biotin
Cat: K009345M - Biotin
Summary:
| 【Product name】：Anti-PPARK2/Parkin Monoclonal Antibody - Biotin | 【Source】：Mouse |
| 【Isotype】：IgG2b | 【Purification】：Affinity purification |
| 【Gene ID】：5071 | 【Swiss Prot】：O60260 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human PARK2 | |
| 【Public Immunogen Range】：81-387aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Parkin, a RING-type E3 ubiquitin-protein ligase, is involved in the ubiquitination pathway and contributes to protection from neurotoxicity induced by unfolded protein stresses. Its ubiquitin–protein ligase activity promotes the degradation of a viariety of proteins including itself. Mutations in Parkin are implicated in the pathogenesis of autosomal recessive familial Parkinson’s disease. It has 8 isoforms produced by alternative splicing.
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