Anti-HDAC4(N-term) Polyclonal Antibody
Cat: K009275P
Summary:
| 【Product name】：Anti-HDAC4(N-term) Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9759 | 【Swiss Prot】：P56524 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:10-100. | |
| 【Immunogen】：A synthetic peptide of human HDAC4 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Verified picture:
Immunohistochemistry of paraffin-embedded Human esophagus cancer with HDAC4 antibody diluted at 1:50.